Dear Colleagues and Friends,

The 6th International Conference of HPV, Polyomavirus and Ultraviolet (UV) Radiation in Skin Cancer will be held under the auspecies of the European Skin Cancer Foundation in Berlin, Germany on October 18th-20th 2012. The aim of this conference is to define future directions of skin cancer research with the main focus on UV radiation and oncogenic viruses [human papillomaviruses (HPV) and polyomaviruses]. Basic research as well as epidemiology and novel therapeutic treatments in skin cancer will be discussed with international experts.

So far, we know that 20% of all cancers are induced by oncogenic viruses. However, it is very likely that these numbers will increase in the future. HPV infect cutaneous and mucosal epithelia and induce benign and malignant lesions. Genital HPV types induce cervical carcinoma and (ano)genital cancers at different sites. The first evidence for the involvement of cutaneous HPV in skin cancer was reported in patients with the rare hereditary disease Epidermodysplasia verruciformis.

The mechanism of genital α-HPV types in cervical carcinogenesis is different compared to cutaneous types (β- and γ-HPV) and better understood. In the last years, several epidemiological and functional findings have supported the role of cutaneous HPV types during skin carcinogenesis. In 2008, a novel Merkel cell polyomavirus (MCV) was identified, which seems to be causally associated with Merkel cell carcinoma (MCC). Several epidemiological and functional studies provide evidence that MCV is the causative agent of MCC.

A particular focus of this conference will be on UV radiation and the oncogenic viruses HPV and MCV. The up-to-date knowledge of both DNA viruses will be summarized and discussed in detail. Additionally, novel diagnostic and therapeutic treatments for skin cancer will be presented and options for the future will be discussed.

The congress will provide lectures by international experts in addition to selected abstracts. Guided poster walks as well as time for fruitful discussions and scientific exchange will be arranged. We hope that this conference will contribute to a better understanding of the broad spectrum of oncogenic virus- induced cancers.

We are looking forward to host and meet you in Berlin in October 2012 and trust that you will have a very pleasant stay.

Ingo Nindl       Eggert Stockfleth       Uwe Trefzer      Jürgen Becker